What type of study is this?

This is a Quantitative Study study.

October 2, 2025DiagnosticsOpen Access

Assessment of Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Interobserver Variability and Contributing Factors

View Full Paper

Ask AI

Bookmark

Authors

Assessment evaluates interobserver variability for TILs in triple-negative breast cancer, highlighting contributing histological factors.

Moderate interobserver agreement was found for stromal TILs, and strong for intratumoral TILs, emphasizing variability challenges.
Quantification of agreement used the intraclass correlation coefficient with ICC values of 0.58 for stromal TILs and 0.71 for intratumoral TILs.
Two consultant pathologists assessed 64 TNBC cases using TIL-WG guidelines to evaluate agreement and identify confounding factors.
Findings call for standardized TIL scoring protocols, as variability was linked to factors like distribution and tumor-stroma interface.

Baharun et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

October 2, 2025DiagnosticsOpen Access

View Full Paper

Ask AI

Bookmark

Authors

Assessment evaluates interobserver variability for TILs in triple-negative breast cancer, highlighting contributing histological factors.

Moderate interobserver agreement was found for stromal TILs, and strong for intratumoral TILs, emphasizing variability challenges.
Quantification of agreement used the intraclass correlation coefficient with ICC values of 0.58 for stromal TILs and 0.71 for intratumoral TILs.
Two consultant pathologists assessed 64 TNBC cases using TIL-WG guidelines to evaluate agreement and identify confounding factors.
Findings call for standardized TIL scoring protocols, as variability was linked to factors like distribution and tumor-stroma interface.

Baharun et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark