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October 3, 2025BMC Cardiovascular Disorders2 citationsOpen Access

A nomogram integrating the CHA2DS2-VASc score for predicting atrial fibrillation recurrence following catheter ablation

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LJLindi JiangYZYuhong ZhongXCXuehai Chen

Key Points

  • The nomogram predicts atrial fibrillation recurrence with a C-index of 0.707, significantly outperforming the CHA2DS2-VASc score alone.
  • Key factors include duration of atrial fibrillation, neutrophil-to-lymphocyte ratio, and left atrial diameter, all linked to recurrence risk.
  • Analysis involved 398 patients divided into recurrence and non-recurrence groups, enhancing prediction accuracy.
  • The model's clinical utility is evident for assessing risk across different atrial fibrillation subtypes and ablation methods.

Abstract

Abstract Objective This study aimed to explore the predictive efficacy of a nomogram based on the congestive heart failure, hypertension, age, diabetes mellitus, prior stroke, transient ischemic attack or thromboembolism, vascular disease, age, and sex category (CHA 2 DS 2 -VASc) score in predicting atrial fibrillation (AF) recurrence following first-time catheter ablation in patients with symptomatic AF. Methods Clinical data of 398 patients were collected and analyzed. Patients were divided into a recurrence group ( n = 81) and a non-recurrence group ( n = 317). Key predictive factors were identified through univariate and multivariate analyses, and a nomogram was subsequently constructed using the R programming language. Results The duration of AF, recurrence during the blanking period, neutrophil granulocyte count, neutrophil-to-lymphocyte ratio (NLR), red blood cell distribution width, and left atrial diameter (LAD) were identified as independent risk factors for AF recurrence ( p 0.5). Conclusion A nomogram incorporating the CHA 2 DS 2 -VASc score was developed to predict the recurrence of AF following ablation. It demonstrated promise in predicting the probability of recurrence 12 months post-ablation. However, further validation is required to confirm its reliability and generalizability.

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Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68dfe93cdaa1363beb049e28https://doi.org/10.1186/s12872-025-05071-2
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