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October 5, 2025Magna Scientia Advanced Research and Reviews

Development and validation of UV spectroscopic method for the estimation of Linagliptin in its pure form and pharmaceutical dosage form

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Authors

VYVarsha YadavRVRishika VaishnavNSN. Srinivasulu

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Overview

This analysis validates a UV spectroscopy method for determining linagliptin levels, indicating strong accuracy and reliability in various dosage forms.

Key Points

  • The developed UV spectroscopy method accurately estimates linagliptin levels in pharmaceutical dosage forms.
  • It shows a linearity range of 1-50 µg/mL with an impressive R2 value of 0.9999.
  • The method achieves low limits of detection and quantification at 0.05657 and 0.1714 µg/mL.
  • No significant interference from excipients indicates robustness for pharmaceutical applications.

Cite This Study

Yadav et al. (2025) studied this question.

synapsesocial.com/papers/68e2537cd6d66a53c24743ffhttps://doi.org/10.30574/msarr.2025.15.1.0113
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analytical Method Development and Validation of RP-HPLC Method for Estimation of Linagliptin in Bulk and Pharmaceutical Dosage Form2025
  2. 2A COMPREHENSIVE REVIEW ON UV AND RP-HPLC ANALYTICAL METHODS FOR QUANTITATIVE DETERMENATION OF LINAGLIPTIN, DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE IN TABLET DOSAGE FORM2026
  3. 3Development of simple uv-spectrophotometric method for the estimation of vildagliptin drug in bulk and its formulation2024
  4. 4Validated Method for Simultaneous Estimation of Linagliptin and Dapagliflozin2025
  5. 5RP-HPLC Method Development and Validation for Analysis of Voglibose and Linagliptinin Tablet Dosage Form2024