Improved Simultaneous Intracranial Vessel Wall Imaging and dynamic MRA Using Low-rank Reconstruction

Acquiring multi-contrast images of intracranial vessels from one single MRI sequence is beneficial for comprehensive neurovascular disease diagnosis. Vessel wall (VW) images and dynamic MRA (dMRA) can be obtained from a time-efficient multi-contrast sequence named iSNAP. However, the previously adopted k-space sharing reconstruction method generated high-quality dMRA but low-quality VW images. In this study, we aim to develop a novel low-rank-based image reconstruction method to reconstruct VW and dMRA from highly undersampled 4D MRI. High quality VW images with sharper wall delineation are obtained, while hemodynamic information from dMRA is preserved.