3D MR Fingerprinting with Fat-navigator-based Motion Correction for Pediatric Imaging

MR Fingerprinting (MRF) simultaneously measures multiple tissue properties within a single scan. Although 2D MRF has been shown to be less sensitivie to motion than conventional imaging, bulk motion is still problematic for longer 3D MR Fingerprinting scans. We propose to integrate 3D fat navigators with 3D MRF acquisitions for motion correction in neuroimaging, especially for non-sedated pediatric imaging. The proposed method was validated in in vivo scans of healthy subjects with various types of motions and in non-sedated infants. We showed that the fat-navigated 3D MRF framework could resolve and correct bulk motions of both healthy volunteers and infants.