Multi-channel CAscaded Multi-scale WAvelet with iterative REfinement (CAMWARE) network for accelerated whole-brain vessel wall imaging

3D MR vessel wall imaging (VWI) is a non-invasive imaging modality for directly assessing intracranial arterial wall diseases. A typical intracranial VWI protocol requires 6-12 minutes per scan to obtain adequate spatial coverage and resolution. Such a long scan time hinders widespread use of VWI in clinical settings. We have developed a multi-channel application-ready intracranial vessel-dedicated CAscaded Multi-level WAvelet REfine (CAMWARE) network that enables a VWI scan within 4 minutes. The proposed network achieved significant improvement in vessel wall delination over conventional compressed sensing reconstruction.