Key points are not available for this paper at this time.
Myelin Volume Fraction (MVF) is an important biomarker of demyelination various diseases Multiple Sclerosis. In this study, we propose a method that provides quantitative MVF maps from routine multiple echo gradient echo acquisitions and dictionary matching. The dictionary is generated using the Hollow Cylindrical Fiber Model (HCFM) and employs both the magnitude signal decay and QSM obtained from the mGRE phase. The obtained maps show both qualitative and quantitative superiority over the standard multiexponential fitting-based myelin water fraction (MWF) maps.
Şişman et al. (2024) studied this question.