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June 5, 2024New England Journal of Medicine460 citations

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair–Deficient Colon Cancer

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MCMyriam ChalabiYVY.L. VerschoorPTPedro Batista Tan

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Abstract

Mismatch repair-deficient (dMMR) tumors can be found in 10 to 15% of patients with nonmetastatic colon cancer. In these patients, the efficacy of chemotherapy is limited. The use of neoadjuvant immunotherapy has shown promising results, but data from studies of this approach are limited.

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Chalabi et al. (2024) studied this question.

synapsesocial.com/papers/68e65f84b6db6435875ed460https://doi.org/10.1056/nejmoa2400634
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