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May 25, 2024Journal of Autoimmunity5 citationsOpen Access

Polymyalgia rheumatica shows metabolomic alterations that are further altered by glucocorticoid treatment: Identification of metabolic correlates of fatigue

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JMJulia E. ManningEHEmma HarrisHMHannah R. Mathieson

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Abstract

In polymyalgia rheumatica (PMR), glucocorticoids (GCs) relieve pain and stiffness, but fatigue may persist. We aimed to explore the effect of disease, GCs and PMR symptoms in the metabolite signatures of peripheral blood from patients with PMR or the related disease, giant cell arteritis (GCA).

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Manning et al. (2024) studied this question.

synapsesocial.com/papers/68e686bfb6db64358760f395https://doi.org/10.1016/j.jaut.2024.103260
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