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April 8, 2024New England Journal of Medicine251 citations

Transcatheter or Surgical Treatment of Aortic-Valve Stenosis

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SBStefan BlankenbergMSMoritz SeiffertRVReinhard Vonthein

Key Points

  • Evidence remains limited regarding optimal treatment selection between transcatheter aortic-valve implantation and surgical replacement for low-risk patients with severe aortic stenosis.
  • Current clinical practice lacks definitive guidance for low-risk individuals who are eligible for both surgical aortic-valve replacement and transcatheter approaches to manage valve disease.
  • Further evaluation of TAVI versus SAVR outcomes in routine clinical settings is needed to establish clear management strategies for low-risk symptomatic patients with aortic stenosis.

Abstract

Among low-risk patients with severe, symptomatic aortic stenosis who are eligible for both transcatheter aortic-valve implantation (TAVI) and surgical aortic-valve replacement (SAVR), data are lacking on the appropriate treatment strategy in routine clinical practice.

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Cite This Study

Blankenberg et al. (2024) studied this question.

synapsesocial.com/papers/68e6febab6db6435876792e3https://doi.org/10.1056/nejmoa2400685
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients2019 · 4,869 citations
  2. 2Sex-Related Differences in Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis2014 · 199 citations
  3. 3Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years2023 · 620 citations
  4. 4Transcatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials2022 · 108 citations
  5. 5Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients2022 · 195 citations