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April 4, 2024Vector-Borne and Zoonotic Diseases2 citations

West Nile Virus Emergence in Germany 2019: Looking for Hidden Human West Nile Virus Infections

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RLRaskit LachmannCDCristina DomingoCFChristina Frank

Key Points

  • Autochthonous West Nile virus transmissions occur with infrequent clinical symptoms, leading to undetected subclinical spread across human populations.
  • Targeted screening evaluates subclinical infection rates through limited-scope blood donor testing alongside serological testing of exposed zoo workers.
  • Serosurvey assessments among high-risk workers highlight silent transmission risks, supporting improved infectious disease surveillance across Germany.

Abstract

Autochthonous human West Nile virus (WNV) infections were notified in the infectious disease surveillance system in Germany in 2018 for the first time and every year since then. Since clinically apparent infections are infrequent, we conducted two studies to investigate subclinical infections of this emerging disease in Germany in 2019 to detect infections not visible to surveillance based on symptomatic infections: limited-scope blood donor testing and a serosurvey among employees at two Berlin zoos with a history of demonstrated WNV infections in animals.

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Cite This Study

Lachmann et al. (2024) studied this question.

synapsesocial.com/papers/68e7068fb6db64358768089fhttps://doi.org/10.1089/vbz.2023.0103
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Circulation dynamics of West Nile virus in Germany, 2023 and 20242026
  2. 2Circulation of West Nile Virus and Usutu Virus in Birds in Germany, 2021 and 2022.2024 · 2 citations
  3. 3Endemic progression of autochthonous West Nile virus infections in Europe2026
  4. 4Spatiotemporally Explicit Epidemic Model for West Nile Virus Outbreak in Germany: An Inversely Calibrated Approach2024 · 7 citations
  5. 5Incorporating vertical transmission into mechanistic modeling of West Nile virus for optimized control in Germany2026