Automatic Liver Segmentation from Multiphase CT Using Modified SegNet and ASPP Module

Abstract Liver cancer is one of the dominant causes of cancer death worldwide. Computed Tomography (CT) is the commonly used imaging modality for diagnosing it. Computer-based liver cancer diagnosis systems can assist radiologists in image interpretation and improve diagnosis speed and accuracy. Since liver segmentation is crucial to such systems, researchers are relentlessly pursuing various segmentation approaches. A clinically viable computer-aided system requires examining multiphase CT images. However, most of the research focuses only on the portal venous phase. In this work, we developed an automatic and efficient Deep Learning (DL) method using SegNet, atrous spatial pyramid pooling module and leaky ReLU layers for liver segmentation from quadriphasic abdominal CT volumes. The proposed method was validated on two datasets, an internal institutional dataset consisting of multiphase CT and a public dataset of portal venous phase CT volumes. The Dice Coefficients (DC) obtained were greater than 96% for the latter dataset and the portal venous phase of the former. For arterial, delayed and plain CT phases of the former dataset, the DC achieved were 94.61%, 95.01% and 93.23%, respectively. Experiments showed that our model performed better than the other state-of-the-art DL models. Ablation studies have revealed that the proposed model leverages the strengths of all the three components that make it up. The promising performance of the proposed method suggests that it is appropriate for incorporation in hepatic cancer diagnosis systems.