PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 27, 2024Haemophilia0 citations

Challenges in ageing persons with haemophilia

View Full Paper
MMMichael MakrisRLRiitta LassilaMKMegan Kennedy

Key Points

Key points are not available for this paper at this time.

Abstract

Abstract As treatments for individuals with inherited bleeding disorders improve, life expectancy increases and is approaching that of the normal population. Concomitant with this we are now seeing the problems of ageing in the bleeding disorder population. Although the clear‐cut association between low clotting factor levels and risk of bleeding is well recognised, a relationship between high levels, some non‐factor therapies and thrombotic risk also exists. The management of thrombosis in persons with inherited bleeding disorders is complex but manageable with modern treatments and collaboration in decision making between health care professionals and patients. Despite the improvements in treatment and reduction in bleeding, mostly musculoskeletal pain continues to be a major issue with advancing age. The management of pain amongst older people with haemophilia who may have multiple comorbidities should involve a person‐centred, holistic, multi‐disciplinary approach to support and optimise long‐term physical functioning and overall quality of life.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Makris et al. (2024) studied this question.

synapsesocial.com/papers/68e7230db6db64358769d2b0https://doi.org/10.1111/hae.14994
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The aging hemophilia patient2025
  2. 2Management of cardiovascular disease in aging persons with haemophilia2016 · 16 citations
  3. 3Ageing with Haemophilia – Comorbidities in Focus2026
  4. 4Haemophilic arthropathy: Diagnosis, management, and aging patient considerations2024 · 7 citations
  5. 5Challenges in Balancing Hemostasis and Thrombosis in Therapy Tailoring for Hemophilia: A Narrative Review2026