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March 5, 2024Journal of Thrombosis and Haemostasis3 citationsOpen Access

Comprehensive domain-specific analysis and immunoglobulin G profiling of anti–factor VIII antibodies using a bead-based multiplex immunoassay

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BPBehnaz PezeshkpoorABAnn‐Cristin BerkemeierKHKerstin Herbst

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Abstract

Antibodies against factor (F)VIII are a major complication in the treatment of patients with severe hemophilia A. The Nijmegen-Bethesda assay (NBA) is the gold standard for detection of neutralizing antibodies (inhibitors), whereas both inhibitors and nonneutralizing antibodies can be detected by immunoassays such as enzyme-linked immunosorbent assay (ELISA) and multiplex bead-based assays.

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Pezeshkpoor et al. (2024) studied this question.

synapsesocial.com/papers/68e75a00b6db6435876d0efchttps://doi.org/10.1016/j.jtha.2024.02.016
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Also Consider

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