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February 22, 2024Science37 citations

An immunogenetic basis for lung cancer risk

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CKChirag KrishnaATAnniina TerviMSMiriam Saffern

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Abstract

Cancer risk is influenced by inherited mutations, DNA replication errors, and environmental factors. However, the influence of genetic variation in immunosurveillance on cancer risk is not well understood. Leveraging population-level data from the UK Biobank and FinnGen, we show that heterozygosity at the

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Cite This Study

Krishna et al. (2024) studied this question.

synapsesocial.com/papers/68e77f57b6db6435876f34cbhttps://doi.org/10.1126/science.adi3808
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