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February 22, 2024Diabetologia35 citationsOpen Access

Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes

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PCPedro CardosoKYKatherine YoungANAnand Thakarakkattil Narayanan Nair

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Abstract

A precision medicine approach in type 2 diabetes could enhance targeting specific glucose-lowering therapies to individual patients most likely to benefit. We aimed to use the recently developed Bayesian causal forest (BCF) method to develop and validate an individualised treatment selection algorithm for two major type 2 diabetes drug classes, sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1-RA).

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Cardoso et al. (2024) studied this question.

synapsesocial.com/papers/68e77f57b6db6435876f351chttps://doi.org/10.1007/s00125-024-06099-3
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