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February 9, 2024Exploration38 citationsOpen Access

Cornea‐SELEX for aptamers targeting the surface of eyes and liposomal drug delivery

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KWKa‐Ying WongYLYibo LiuMWMan‐Sau Wong

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Abstract

Cornea is the major barrier to drug delivery to the eye, which results in low bioavailability and poor efficacy of topical eye treatment. In this work, we first select cornea-binding aptamers using tissue-SELEX on pig cornea. The top two abundant aptamers, Cornea-S1 and Cornea-S2, could bind to pig cornea, and their

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Wong et al. (2024) studied this question.

synapsesocial.com/papers/68e79c4cb6db64358770b845https://doi.org/10.1002/exp.20230008
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