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October 18, 2025Tropical Medicine and Infectious Disease0 citationsOpen Access

Serology-Based Screening and Prevalence of Schistosomiasis, Strongyloidiasis, and Chagas Disease in Migrants Living with HIV: Results from a 10-Year Retrospective Cohort in an Italian Tertiary Healthcare Center

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ABAnna BarbieroRPRiccardo PaggiSTSasha Trevisan

Key Points

  • Seroprevalence rates of schistosomiasis, strongyloidiasis, and Chagas disease were found to be 13.6%, 0%, and 5.3% among migrants living with HIV.
  • Risk for strongyloidiasis, schistosomiasis, and Chagas disease was identified in 87.3%, 33.9%, and 54.6% of participants respectively.
  • Only 25.9% of the individuals at risk for schistosomiasis were screened, indicating significant underdiagnosis in this population.
  • This study underscores the urgent need to improve awareness and screening efforts of neglected tropical diseases in healthcare settings.

Abstract

Background: Migration phenomena from low- to high-income countries have been constantly increasing in the past years, and migrants living with HIV (MLHIVs) currently represent a non-negligible proportion of the population living with HIV in the European setting. When taken into care, MLHIVs should be screened for tropical diseases capable of asymptomatically persisting for years and leading to severe and/or chronic complications, especially in immunocompromised populations. Methods: We conducted a retrospective study aimed at analyzing the screening ratios and seroprevalences of strongyloidiasis, schistosomiasis, and Chagas disease among MLHIVs who attended a tertiary care hospital outpatient clinic in Florence, Italy. Results: Between 2014 and 2023, 251 MLHIVs were enrolled, of which 85 (33.9%), 137 (54.6%), and 219 (87.3%) were at risk for schistosomiasis, Chagas disease, and strongyloidiasis, respectively. Among individuals at risk for each of these parasitic diseases, 43.4% were screened for strongyloidiasis, 25.9% for schistosomiasis, and 65.0% for Chagas disease, with a seroprevalence of 5.3%, 13.6%, and 0%, respectively. Conclusions: While confirming the relevant burden of neglected parasitic diseases in the MLHIV population, our results suggest the need to improve awareness of these diseases even in the specialist context in order to reduce underdiagnoses and the risk of severe complications, especially in particularly vulnerable groups of the population.

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Cite This Study

Barbiero et al. (2025) studied this question.

synapsesocial.com/papers/68f3d0c11cb4135751d12adfhttps://doi.org/10.3390/tropicalmed10100294
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