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November 1, 2025Journal of the National Comprehensive Cancer Network0 citations

NCCN Guidelines® Insights: Breast Cancer, Version 5.2025

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WGWilliam J. GradisharMMMeena S. MoranJAJame Abraham

Key Points

  • To summarize recent updates in the NCCN Guidelines for Breast Cancer treatment.
  • Review of NCCN Guidelines for Breast Cancer Version 5.2025.
  • Focus on updates regarding treatment landscape and recommendations.
  • Updates include recommendations for locoregional therapy and surveillance.
  • New insights on neoadjuvant and adjuvant systemic therapy have been highlighted.

Abstract

The treatment landscape of invasive early-stage and metastatic breast cancer is evolving constantly. These NCCN Guidelines Insights focus on recent updates included in the most recent version (version 5.2025) of the NCCN Guidelines for Breast Cancer specific to workup, locoregional therapy, surveillance, and systemic neoadjuvant/adjuvant therapy recommendations for invasive, nonmetastatic breast cancer.

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Gradishar et al. (2025) studied this question.

synapsesocial.com/papers/6925435ec0ce034ddc35803fhttps://doi.org/10.6004/jnccn.2025.0053
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