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November 30, 2025Journal of Cardiothoracic Surgery2 citationsOpen Access

Catastrophic antiphospholipid syndrome following surgery for Libman–Sacks endocarditis: A case report and literature review

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YLYinxia LiQHQingyu HuangRSRui Shen

Key Points

  • Catastrophic antiphospholipid syndrome emerged post-surgery, with significant implications for patient outcomes.
  • Failure to identify APS risk factors before surgery may lead to serious complications in valve lesion cases.
  • Case presentation involved a patient with Libman-Sacks endocarditis and underscored the importance of immunologic assessment.
  • Continued awareness of APS can guide timely interventions and improve surgical outcomes.

Abstract

This case highlights the importance of recognising APS as the systemic autoimmune basis of LSE and the need for early immunologic and thrombotic evaluation in patients with unexplained valve lesions. Failure to identify underlying APS before surgery may increase the risk of CAPS and poor outcomes.

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Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/692b944c1d383f2b2a378d37https://doi.org/10.1186/s13019-025-03692-4
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