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November 30, 2025Journal of Hand Surgery (European Volume)0 citations

Anterior interosseous nerve transfer combined with cubital and ulnar tunnel release for severe ulnar nerve compression

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PLPo-Hao LienCLChun-Wei LiCHChung-Cheng Hsu

Key Points

  • Sustained clinical and electrophysiological improvements were observed by 6 months post-surgery for ulnar neuropathy.
  • Significant metrics include improved gripping and pinching forces along with two-point discrimination.
  • Prospective analysis of 28 patients with severe ulnar neuropathy due to various aetiologies was conducted.
  • Effectiveness of combined nerve transfer with releases promotes its adoption as standard care for chronic conditions.

Abstract

Introduction: We investigated the outcomes of patients with severe ulnar nerve compression who underwent anterior interosseous nerve transfer combined with cubital and ulnar tunnel release. Methods: Twenty-eight patients with McGowan IIB or III ulnar neuropathy caused by compression and with compound muscle action potentials of the ulnar intrinsics less than 3 mV were prospectively recruited for outcome analysis. Clinical signs of ulnar palsy, two-point discrimination tests, gripping and pinching force and electrophysiological studies were recorded over a 2 year follow-up. Results: Significant improvement was observed in most features by 6 months after surgery. Subgroup analysis by aetiology at 2 years revealed no statistically significant differences in the recorded variables between individuals with previous trauma and those with idiopathic ulnar palsy. Conclusion: Anterior interosseous nerve transfer, along with cubital and ulnar tunnel release, results in sustained clinical and electrophysiological improvements in patients with severe chronic ulnar nerve compression, which encourages its adoption as a standard treatment for severe chronic ulnar nerve compression. Level of evidence: IV

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Cite This Study

Lien et al. (2025) studied this question.

synapsesocial.com/papers/692b9da01d383f2b2a37a27chttps://doi.org/10.1177/17531934251381023
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