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December 11, 2025New Journal of Chemistry3 citations

Copper(II) Complexes of Dipica and Its Derivatives as Biomimetic Models for Phenoxazinone Synthase: Probing the Effect of Central N-cycloalkyl Rings on Reactivity

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YGY. S. S. GaneshKDKarthik DevarajNPNarasimman Palani

Key Points

  • The research aims to explore copper(II) complexes as biomimetic models for the phenoxazinone synthase enzyme.
  • Synthesis of a series of copper(II) complexes incorporating tridentate 3N donor ligands.
  • Evaluation of the complexes for their properties as models for phenoxazinone synthase.
  • Copper(II) complexes demonstrate varying reactivity based on their structural components.
  • The presence of central N-cycloalkyl rings affects reactivity in the complexes.

Abstract

A series of copper(II) complexes 1–4 of type Cu(L1–L4)Cl2 incorporating tridentate 3N donor ligands L1–L4 have been synthesized and evaluated as biomimetic models for phenoxazinone synthase enzyme (PHS). The ligands...

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Cite This Study

Ganesh et al. (2025) studied this question.

synapsesocial.com/papers/694019342d562116f28f6d30https://doi.org/10.1039/d5nj04085j
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