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December 8, 2025JAMA13 citations

Trends in Vitamin K Administration Among Infants

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KSKristan ScottChildren's Hospital of PhiladelphiaEMEvan W. MillerBerkeley CollegeJCJennifer F. CulhaneYale University

Key Points

  • Increased nonreceipt of intramuscular vitamin K suggests a concerning trend among infants.
  • Analysis indicates that certain factors may determine vitamin K administration.
  • Observational analysis reveals rising trends in vitamin K administration among infants in the US.
  • Understanding the factors behind nonreceipt of vitamin K may inform public health strategies.

Abstract

This study evaluates whether the proportion of newborns in the US not receiving intramuscular vitamin K has increased in recent years and identifies factors associated with nonreceipt.

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Cite This Study

Scott et al. (2025) studied this question.

synapsesocial.com/papers/69401f142d562116f28fa62bhttps://doi.org/10.1001/jama.2025.21460
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vitamin K Prophylaxis in Newborns and Bleeding in Infancy2026
  2. 2Oral Vitamin K—US Newborns Need an FDA-Approved Option2026
  3. 3Neonatal Vitamin K Refusal and Nonimmunization2014 · 71 citations
  4. 4Reasons for Refusal of Newborn Vitamin K Prophylaxis: Implications for Management and Education2016 · 49 citations
  5. 5Lack of documented prophylactic vitamin K administration in newborns: incidence, predictors, and bleeding outcomes in a large healthcare network population2026