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December 2, 2025Annals of Nutrition and Metabolism1 citations

Machine Learning Based Analysis of Diagnostic Markers for Malnutrition

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NONedim OngunMÇMustafa ÇakırOOOkan Oral

Key Points

  • Machine learning predicts malnutrition, achieving high accuracy rates and Kappa values in clinical scenarios.
  • Key predictive variables included weight loss and body mass index, which were significant per diagnostic measures.
  • Logistic regression and decision tree analysis were utilized to establish the effectiveness of the proposed model.
  • The model's efficiency and accuracy for malnutrition diagnosis hold potential for improving healthcare outcomes.

Abstract

Introduction Malnutrition leads to negative health outcomes such as delayed recovery, increased hospital stays, and higher costs. The study aimed to develop a predictive tool to diagnose malnutrition using patient data, including anthropometric, phenotypic, and laboratory information. Methods A cohort of 252 adult patients was assessed at a tertiary hospital. Logistic regression and decision tree analysis were applied to evaluate the role of the data in predicting the risk of malnutrition. The performances of the models were tested with Akaike Information Criterion, Null Deviance, Residual Deviance, Accuracy and Kappa metrics and the statistical significance of the variables was evaluated with Wald-Z test. Attribute importance ranking was obtained by Bootstrap Optimized Random Univariate Tree Analysis (BORUTA) algorithm. Results A total of 252 patients, 125 female (49.6%) and 127 male (50.4%), were included in the study. The mean age was 72.57±13.6 years. Malnutrition was diagnosed in 174 patients (69%). According to the equations, the most important characteristics were determined as hand grip strength (HG), weight loss (WL), body mass index (BMI) and gender. The model achieved high accuracy (89.8%) and a Kappa value of 0.79, demonstrating its potential for clinical application. Conclusion Machine learning model offers a faster, more efficient alternative to traditional diagnostic tools. The study concludes that machine learning-based models provide superior prediction performance and could significantly enhance the efficiency and accuracy of malnutrition diagnosis in healthcare.

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Cite This Study

Ongun et al. (2025) studied this question.

synapsesocial.com/papers/6940275a2d562116f28ffb77https://doi.org/10.1159/000549549
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