PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 10, 2026npj Digital Medicine0 citationsOpen Access

ScarElastic: continuous elasticity field modeling for myocardial scar delineation in LGE-CMR

RZRongjun ZouYLYugui LiNZNa Zhou

Key Result

ScarElastic improved scar delineation in LGE-CMR by up to +3.1% in Dice coefficient and -1.8 mm in HD95, particularly enhancing accuracy in hypertrophic cardiomyopathy cases.

Key Points

  • The aim is to enhance myocardial scar delineation by modeling it as a continuous elasticity field.
  • Developed a novel framework called ScarElastic.
  • Evaluated on three public benchmarks: STACOM-LGE 2018, MyoPS 2020, and MS-CMRSeg 2019.
  • Compared performance against state-of-the-art scar delineation methods.
  • Achieved up to +3.1% improvement in Dice coefficient.
  • -1.8 mm reduction in Hausdorff distance (HD95).
  • +0.06 gain in structural continuity score, especially in hypertrophic cardiomyopathy cases.

Structured PICO

Does ScarElastic improve myocardial scar delineation accuracy and structural continuity compared to state-of-the-art binary segmentation methods in LGE-CMR?

P
Population
182 subjects with LGE-CMR scans from three public benchmark datasets (STACOM-LGE 2018 n=102, MyoPS 2020 n=45, MS-CMRSeg 2019 n=35), including patients with hypertrophic cardiomyopathy (HCM) or myocardial infarction (MI).
I
Intervention
ScarElastic, a continuous elasticity field modeling framework for myocardial scar delineation
C
Comparator
State-of-the-art binary segmentation methods (e.g., ScarNet, U-Net, nnU-Net) and traditional threshold-based methods (n-SD, FWHM)
O
Outcome
Dice Similarity Coefficient (DSC), 95th Percentile Hausdorff Distance (HD95), and Structural Continuity Score (SCS)surrogate

ScarElastic, a continuous elasticity field model, significantly improves the accuracy and anatomical topology preservation of myocardial scar segmentation on LGE-CMR compared to conventional binary methods.

Abstract

Late gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) imaging is a crucial modality for identifying myocardial scar, yet current binary segmentation approaches often fail to capture the continuous and heterogeneous nature of fibrosis. In this study, we propose ScarElastic, a novel framework that models scar as a continuous elasticity field, enabling the preservation of myocardial wall topology and more faithful delineation of diffuse or patchy lesions. Across three public benchmarks (STACOM-LGE 2018, MyoPS 2020, and MS-CMRSeg 2019), ScarElastic consistently outperformed state-of-the-art methods, achieving up to +3.1% Dice improvement, -1.8 mm reduction in HD95, and a +0.06 gain in structural continuity score. These gains were particularly pronounced in hypertrophic cardiomyopathy (HCM) cases with complex scar morphology. Beyond quantitative accuracy, the elasticity field provides interpretable maps that correlate with clinical indices such as scar burden and transmural extent, suggesting strong potential for integration into clinical workflows.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Zou et al. (2025) studied this question. ScarElastic improved scar delineation in LGE-CMR by up to +3.1% in Dice coefficient and -1.8 mm in HD95, particularly enhancing accuracy in hypertrophic cardiomyopathy cases.

synapsesocial.com/papers/6963221991e05aa366cb893dhttps://doi.org/10.1038/s41746-025-02163-3
Ask AI
Helpful
Bookmark
Share
View Full Paper