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January 18, 2026Journal of Clinical Medicine3 citationsOpen Access

WADD-SEPD Consensus on Psychological Treatment of Dual Disorders I: General Recommendations, Most Used Therapies, and Severe Mental Disorders

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ABA BenitoSJSusana Jiménez-MurciaJTJudit Tirado-Muñoz

Key Points

  • The aim is to compile evidence and recommendations on psychological treatment for dual disorders (DDs).
  • Implemented nominal group technique and Delphi method for consensus building
  • Synthesized evidence on psychotherapy effectiveness
  • Compiled recommendations for severe dual mental disorders
  • Psychological treatments are effective, especially when integrated
  • Motivational interviewing and cognitive behavioral therapy have strong support
  • Multicomponent strategies are the best approach
  • Recommendations include family involvement for bipolar disorder
  • More empirical evidence and clinical trials are needed to address gaps

Abstract

Background/Objectives: The treatment of dual disorders (DDs) must be comprehensive and multidisciplinary. There is evidence supporting the effectiveness of psychotherapy in their treatment. However, clinical guidelines, consensus statements, and reviews on the treatment of DDs typically devote considerably less space to psychological therapy than to pharmacological therapy. Therefore, this work aimed to synthesize the available evidence, recommendations, and clinical experience on the psychological treatment of DDs to reach a consensus. Methods: Two consensus methods were sequentially implemented: the nominal group technique and the Delphi method. Results: The first part of this consensus review encompassed a compilation of general recommendations for the psychological treatment of DDs, evidence on the efficacy of the most frequently used therapies, and recommendations for the psychological treatment of severe dual mental disorders. These disorders include schizophrenia and other psychotic disorders, bipolar disorders, depressive disorders, and obsessive compulsive disorders. Conclusions: (1) Psychological treatment is effective; (2) integrated psychological treatment is more effective; (3) motivational interviewing, cognitive behavioral therapy, and relapse prevention are the psychological interventions with the most supporting evidence; (4) the best alternative is multicomponent strategies; (5) the most frequently studied severe mental disorders are schizophrenia and depression; (6) for dual schizophrenia, motivational interviewing and integrated cognitive behavioral therapy combined with other components are recommended; (7) for dual depression, cognitive behavioral therapy with relapse prevention or motivational interviewing is recommended; (8) for dual bipolar disorder, group therapies with psychoeducation or relapse prevention and inclusion of the family, contingency management, and family intervention are recommended; (9) more empirical evidence is needed, especially for obsessive compulsive and schizoaffective disorders; and (10) more randomized clinical trials are needed to improve current methodological limitations.

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Cite This Study

Benito et al. (2026) studied this question.

synapsesocial.com/papers/696c772aeb60fb80d1395781https://doi.org/10.3390/jcm15020730
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