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January 18, 2026AIDS and Behavior0 citationsOpen Access

Sexual Relationship Typologies, Multilevel Determinants, and HIV Among Adolescent Mothers in Eastern and Southern Africa: A Multilevel Latent Class Analysis

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LGLuwam T. GebrekristosPRPetrica RouseMSMarie C.D. Stoner

Key Points

  • Identify and characterize sexual relationship typologies among adolescent mothers and their multilevel determinants to inform interventions for reducing HIV risk.
  • Analyzed data from 2,761 adolescent mothers aged 15–19 years from 9 Eastern and Southern Africa countries.
  • Conducted multilevel latent class analysis to identify relationship typologies.
  • Used multinomial logistic regression to characterize typologies by individual and community-level predictors.
  • Applied generalized estimating equations to calculate prevalence ratios of HIV related to each relationship typology.
  • Identified three relationship typologies: married with minimal transactional sex (61%), unmarried peer partnership (30%), and working and high transactional sex (9%).
  • Observed that married with minimal transactional sex had a 51% lower HIV prevalence compared to unmarried peer partnerships.
  • Established two community-level classes: high age-disparate marriage (49%) and low marriage (51%).
  • Found that low-wealth communities had higher odds of belonging to high age-disparate marriage classes.

Abstract

Abstract In Eastern and Southern Africa (ESA), there is heterogeneity within adolescent mothers’ (AMs’) sexual relationships. However, existing studies focus on single relationship characteristics, even though these characteristics do not operate in isolation. Moreover, no studies have examined multilevel predictors of AMs’ relationships. Identifying and characterizing typologies by multilevel factors can inform targeted interventions to lower HIV risk. Data are from the Population-based HIV impact Assessment (PHIA) Project on AMs (15–19 years) from 9 ESA countries ( N = 2,761). We conducted multilevel latent class analysis to identify relationship typologies at the AM and community (PHIA cluster) levels, multinomial logistic regression to characterize typologies by multilevel predictors, and multivariable generalized estimating equations (GEE) log-binomial regression to calculate prevalence ratios of HIV for relationship typologies. There were 3 typologies: married with minimal transactional sex (61%), unmarried peer partnership (30%), and working and high transactional sex (9%). Individual-level (i.e., age, school enrollment, low-wealth household, number of sexual partners) and community-level factors (i.e., urbanicity and proportion of low-wealth households) were associated with typologies. Married with minimal transactional sex was associated with a 51% lower HIV prevalence compared to the unmarried peer partnership (adjusting for multilevel factors). We also identified 2 PHIA cluster-level classes: high age-disparate marriage (49%) and low marriage (51%). Low-wealth communities had higher odds of being high age-disparate marriage communities. Results suggest that AMs’ relationships fall into 3 distinct typologies and 2 community-level classes. Further, HIV prevalence varies across relationship typologies. Utilizing tailored approaches could optimize interventions that reduce AMs’ HIV risk in ESA.

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Cite This Study

Gebrekristos et al. (2026) studied this question.

synapsesocial.com/papers/696c774feb60fb80d13958c7https://doi.org/10.1007/s10461-025-05024-y
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