PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 18, 2026Clinical Case Reports0 citationsOpen Access

Integrating Artificial Intelligence Into Exposure Therapy: A One Year Follow‐Up Case Report of Emetophobia With Comorbid Panic Disorder

View Full Paper
UKU. Selen Kilic

Key Points

  • This research aims to explore the effectiveness of integrating artificial intelligence into CBT for treating emetophobia with comorbid panic disorder.
  • Case report of a 24-year-old woman with emetophobia and panic disorder.
  • Utilized a structured CBT protocol that included exposure therapy and response prevention.
  • Integrated the ChatGPT AI tool for interactive sessions to enhance engagement and reduce avoidance behaviors.
  • Tracked treatment progress using validated self-report measures at baseline and one-year follow-up.
  • Significant symptom reduction observed across multiple domains including panic and avoidance behaviors.
  • By treatment end, the client no longer relied on safety behaviors and showed improved tolerance to discomfort.
  • Improvements were maintained at one-year follow-up, indicating lasting benefits from the treatment.

Abstract

ABSTRACT Emetophobia is a specific phobia characterized by an intense fear of vomiting, often accompanied by panic attacks, hypervigilance to bodily sensations, and avoidance behaviors. This case study describes the Cognitive Behavioral Therapy (CBT)‐based treatment of a 24‐year old woman with Emetophobia and comorbid panic disorder. Her symptoms caused significant impairment, leading her to avoid social settings, public spaces, and situations linked to vomiting (e.g., dining out, public transport, certain media content). Treatment followed a structured CBT protocol for specific phobias, including psychoeducation, cognitive restructuring, exposure therapy, response prevention and attention‐shifting techniques. A novel feature of the intervention was the inclusion of brief, spoken interactions in English with a speech‐based artificial intelligence tool ChatGPT. As English was not the client's first language, these interactions required increased cognitive effort, serving as a structured external distraction that facilitated habituation by helping her remain in anxiety‐provoking situations without relying on safety behaviors. Treatment progress was tracked using validated self‐report measures including the Specific Phobia of Vomiting Inventory, the Emetophobia Questionnaire‐13 and Panic Disorder Severity Scale. Substantial symptom reduction was observed across domains, with improvements maintained at one‐year follow‐up. By the end of therapy, the client no longer depended on safety behaviors and demonstrated greater tolerance for bodily sensations and uncertainty. This case highlights the potential of CBT for treating Emetophobia and suggests that the integration of artificial intelligence, when applied with clear clinical rationale, may improve attentional flexibility and enhance treatment engagement.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

U. Selen Kilic (2026) studied this question.

synapsesocial.com/papers/696c77afeb60fb80d1395e12https://doi.org/10.1002/ccr3.71715
Ask AI
Helpful
Bookmark
Share
View Full Paper