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January 18, 2026New Journal of Chemistry0 citations

Amphotericin B Encapsulation and Controlled Release from PSSAb-PMAV Micelles for Anti-Leishmanial Treatment

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MKMegha KeshariBanaras Hindu UniversitySJSheetal JaiswalBanaras Hindu UniversityASAbhishek Kumar SinghFriedrich-Alexander-Universität Erlangen-Nürnberg

Key Points

  • The aim is to investigate amphotericin b encapsulation and release from PSSAb-PMAV micelles for treating leishmaniasis.
  • Synthesis of amphiphilic block copolymers for micelle formation
  • Encapsulation of amphotericin b in micelles
  • Assessment of drug release kinetics
  • Evaluation of anti-leishmanial efficacy
  • Successful encapsulation of amphotericin b in micelles
  • Controlled release profile observed in vitro
  • Enhanced anti-leishmanial activity compared to unencapsulated drug

Abstract

Amphiphilic block copolymers are increasingly utilised in nanomedicine due to their ability to self-assemble into micelles that effectively encapsulate hydrophobic drugs. In this study, we present the synthesis and comprehensive...

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Cite This Study

Keshari et al. (2026) studied this question.

synapsesocial.com/papers/696c77f1eb60fb80d139621dhttps://doi.org/10.1039/d5nj04314j
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