Abstract Background: Varicose veins are a common cause of chronic venous disorders (CVD). Despite a robust overview of valve prevalence, paucity exists in terms of precise positioning or distances of these valves, particularly concerning their relationship to the saphenofemoral junction, despite the presumption of primary and post-thrombotic VE disorders. Objective: To investigate the etiology of femoral vein incompetence as a central element within the natural progression of CVD. Methods: We conducted an investigation involving 80 patients with primary varicose veins, encompassing 87 limbs. Doppler ultrasonography (US) was performed on a total of 80 lower extremities of patients. Results: Patients with higher CEAP clinical classes exhibited combined valvular incompetence, while those with ulcers had perforator incompetence. Hypertension was significantly associated with severity categories (p 0.001), with the highest prevalence in C4-C6. Heart failure, PAD, skeletal or joint leg diseases, and chronic obstructive pulmonary disease (COPD), which were more prevalent in severe CVD cases, were also identified. Conclusions: These results could encourage a proactive approach in patients with CVD, and additional screening for diabetes mellitus, hypertension, heart failure, skeleton or joint disease, and emphysema may need to be performed in these patients.
International Journal of Medical Science and Advanced Clinical Research (IJMACR) (2025) studied this question.