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January 20, 2026BMC Microbiology0 citationsOpen Access

The antiparasitic drug Nitazoxanide enhances the susceptibility of Candida albicans to fluconazole

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JPJuan PanZYZhuocheng YaoJZJia Zhang

Key Points

  • To investigate the effect of nitazoxanide on the susceptibility of Candida albicans to fluconazole.
  • Experimental evidence collection using laboratory models
  • Assessment of Candida albicans susceptibility to fluconazole with and without nitazoxanide
  • Nitazoxanide significantly enhances the susceptibility of Candida albicans to fluconazole
  • This combination may improve the effectiveness of antifungal treatments.

Abstract

The results in this study provide preliminary experimental evidence supporting the potential clinical application of NTZ combined with FLC. This regimen may improve FLC efficacy and represents an exploratory approach for optimizing antifungal treatment strategies.

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Cite This Study

Pan et al. (2026) studied this question.

synapsesocial.com/papers/696f1ac19e64f732b51ef0c2https://doi.org/10.1186/s12866-025-04701-1
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