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January 22, 2026Medicine0 citationsOpen Access

Simultaneous transcatheter aortic and mitral valve-in-valve replacement: A case report

YMYue MaoYZYang ZhanRLRong Li

Key Result

The patient showed improved quality of life and no adverse cardiovascular events one year after simultaneous aortic and mitral valve-in-valve replacement.

Key Points

  • The aim is to report on the challenges and outcomes of combined transcatheter aortic and mitral valve-in-valve replacement following bioprosthetic valve failure.
  • Case report of a patient with bioprosthetic valve failure
  • Used 3-dimensional echocardiography for diagnosis
  • Focus on perioperative care including monitoring and rehabilitation
  • Mitral regurgitation was slight post-operation; aortic flow normalized
  • No adverse cardiovascular events at 1-year follow-up
  • Patient's quality of life improved after the procedure

Structured PICO

P
Population
1 patient with bioprosthetic valve failure
I
Intervention
Simultaneous transcatheter aortic and mitral valve-in-valve replacement with integrated perioperative care
O
Outcome
Valve function (mitral regurgitation, aortic valve flow velocity and differential pressure) and quality of life at 1 yearsurrogate

Simultaneous transcatheter aortic and mitral valve-in-valve replacement with integrated perioperative care can be successfully performed with good 1-year outcomes in patients with bioprosthetic valve failure.

Abstract

Rationale: There are fewer reports in China about re-performing combined transcatheter transcatheter aortic and mitral valve-in-valve replacement after bioprosthetic valve failure. Due to the higher difficulty of the combined secondary bivalve procedure and the greater risk of pericardial tamponade and malignant arrhythmias, the professional demands on the surgeon and team are extremely high. It is particularly important to provide quality perioperative care for such patients. Patient concerns: This study reports a case of bioprosthetic valve failure after undergoing transcatheter aortic and mitral bicuspid valve-in-valve replacement.After active treatment and careful care, the patient recovered well after the operation and had a good quality of life during the 1 year follow-up period. Diagnoses: Valve function was measured by 3-dimensional echocardiography. Interventions: The key points of perioperative care include: close monitoring of the patient’s condition and provision of first aid before surgery; close monitoring of hemodynamic parameters, management of fluid balance, provision of respiratory support and oxygen therapy management, prevention of complications and early cardiac rehabilitation after surgery. Outcomes: On the 16th day after the operation, the 3-dimensional echocardiogram showed that the mitral regurgitation was slight. Mitral regurgitation was slight, and aortic valve flow velocity and differential pressure were normalized. At 1 year follow-up, there were no adverse cardiovascular events and quality of life improved. Lessons: For patients undergoing simultaneous transcatheter bivalve replacement with multiple comorbidities, focus should be placed on constructing an integrated perioperative intervention pathway to comprehensively improve clinical tolerance and control the risk of complex cases.

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Cite This Study

Mao et al. (2026) studied this question. The patient showed improved quality of life and no adverse cardiovascular events one year after simultaneous aortic and mitral valve-in-valve replacement.

synapsesocial.com/papers/6971bd90642b1836717e23cchttps://doi.org/10.1097/md.0000000000045726
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