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January 22, 2026IEEE Transactions on Biomedical Engineering0 citations

PINN-EM: Physics-Guided Disease Progression Model of Geographic Atrophy

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DLDmitrii LachinovTPThomas PinetzHBHrvoje Bogunović

Key Points

  • The aim is to develop a model to simulate disease progression using physics-based methods.
  • Developed a spatio-temporal disease progression model
  • Applied parametrized PDE fitting procedures
  • Utilized empirical datasets from various domains
  • Demonstrated effective modeling of disease progression
  • Showed versatility across different empirical datasets

Abstract

The proposed spatio-temporal disease progression model and PINN-EM fitting procedure can be applied across diverse domains facing the challenge of fitting parametrized PDE to the empirical datasets.

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Cite This Study

Lachinov et al. (2026) studied this question.

synapsesocial.com/papers/6971bd90642b1836717e23e5https://doi.org/10.1109/tbme.2026.3655164
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