PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 22, 2026Journal of Clinical Medicine0 citationsOpen Access

Preoperative Metabolic Risk Factors and Outcomes in Living Donor Liver Transplant in HBV Recipients

View Full Paper
SDSafiye Koçulu DemirASAyfer SERİNBBBirkan Bozkurt

Key Points

  • Evaluate how preoperative metabolic risk factors impact postoperative outcomes in HBV patients receiving liver transplants.
  • Retrospective analysis of 319 HBV patients undergoing living donor liver transplantation from 2004 to 2019.
  • Classification into two groups based on preoperative risk factors: group 1 (no risk factors) and group 2 (with risk factors).
  • Comparison of postoperative complications such as mortality, infections, and bleeding between the two groups using various statistical tests.
  • No significant differences were found in postoperative mortality (8.87% vs. 9.52%, p = 0.62) between groups.
  • Infections and bleeding complications showed similar rates with p-values indicating no statistical significance.
  • Bloody complications were more frequent in patients with obesity but did not reach significance (p = 0.08).

Abstract

Objective: Additional preoperative risk factors may influence the prognosis of patients diagnosed with HBV. This study aims to compare the effects of cirrhosis patients with HBV with and without risk factors on post-transplant follow-ups and postoperative complications. Materials and Method: The study included patients with HBV who underwent living donor liver transplantation (LDLT) at Demiroğlu Bilim University, Şişli Liver Transplant Center, Istanbul, Türkiye, between 2004 and 2019. The data from 319 patients were retrospectively analyzed. Those without preoperative risk factors were classified as group 1 (n = 214), and those with risk factors were classified as group 2 (n = 105). These patients were compared in terms of complications during their postoperative follow-up. The Student’s t-test, ANOVA test, Mann–Whitney U test, Kruskal–Wallis test, chi-squared test, and Fisher’s exact test were used, and p < 0.05 was considered statistically significant. Results: When group 1 and group 2 were compared in terms of postoperative mortality, infections, bleeding complications, and biliary system complications, no statistically significant difference was found (8.87% vs. 9.52% p = 0.62), (28.80% vs. 20.24%, p = 0.95), (6.10% vs. 8.70%, p = 0.35), (12.7% vs. 9.60% p = 0.19, respectively). Although bleeding complications were numerically found more frequent in patients with obesity, this difference did not reach statistical significance (23.02% vs. 6.10% p = 0.08). Conclusions: Obesity was not significantly associated with postoperative complications and may be influenced by accompanying comorbidities.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Demir et al. (2026) studied this question.

synapsesocial.com/papers/6971bdec642b1836717e2950https://doi.org/10.3390/jcm15020811
Ask AI
Helpful
Bookmark
Share
View Full Paper