Conclusions: ACEs are significant contributors to the psychopathogenesis of chronic pain. They disrupt neurobiological regulation, intensify emotional vulnerability, and alter pain processing pathways. The biopsychosocial model provides a comprehensive framework for understanding these interactions. Trauma-informed care and targeted education - centered on emotional awareness and conscious pain regulation - are essential for improving treatment outcomes and promoting holistic recovery. Recognizing the long-term impact of ACEs is vital for developing effective rehabilitation strategies and empowering affected individuals.
Butska et al. (2025) studied this question.