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January 23, 20260 citationsOpen Access

Translating System Dynamics into Clinical Strategy Conceptually informed by the Universal Resonance Model (URM)

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ADAnita Domargård

Key Points

  • The research aims to integrate system dynamics and the Universal Resonance Model into clinical reasoning for better treatment strategies.
  • Examined how system dynamics concepts relate to clinical practices
  • Evaluated features like variability and recovery speed in patient responses
  • Discussed implications for therapeutic interventions based on dynamic processes
  • Emphasizes shifting focus from static biomarkers to dynamic patient behavior
  • Finds that treatment success can vary greatly between patients due to different system behaviors
  • Encourages more context-sensitive approaches in clinical decision-making

Abstract

This paper explores how concepts from systems dynamics and the Universal Resonance Model (URM) can be translated into practical clinical reasoning. Rather than treating disease as a static state defined by thresholds and categories, it interprets illness as a dynamic process shaped by instability, recovery, and adaptive capacity. The text shows how features such as variability, recovery speed, timing sensitivity, and proximity to transition can inform therapeutic strategy—guiding when to intervene, how strongly to perturb a system, and why the same treatment may succeed in one patient and fail in another. It does not propose new clinical protocols, but offers an interpretive layer that helps clinicians understand treatment response, resistance, and delayed effects in complex diseases. By shifting focus from static biomarkers to system behavior, the paper provides a conceptual bridge between precision medicine and dynamic medicine, supporting more context-sensitive and timing-aware clinical decision-making.

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Cite This Study

Anita Domargård (2026) studied this question.

synapsesocial.com/papers/69730f59c8125b09b0d1f2f2https://doi.org/10.5281/zenodo.18329385
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