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January 23, 20260 citations

Evaluating the Cepheid Xpert TB/LTBI research-use-only assay for detection of active and latent Mycobacterium tuberculosis infection.

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BSBrittney SweetserHNHoang Quan NguyenHDHai Dang

Key Points

  • The research aims to assess the accuracy of the Cepheid Xpert TB/LTBI assay in detecting active and latent tuberculosis infections.
  • Evaluated the accuracy of the Xpert TB/LTBI assay against WHO standards.
  • Compared assay performance in identifying active TB and latent TB infection.
  • Xpert TB/LTBI exceeded WHO-recommended minimum accuracy targets for TB screening.
  • Identified a need for improvement in distinguishing active TB from latent infections.

Abstract

Xpert TB/LTBI exceeded World Health Organization (WHO)-recommended minimum accuracy targets for a TB screening test. However, further refinement is needed to improve its ability to distinguish active TB from LTBI.

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Cite This Study

Sweetser et al. (2026) studied this question.

synapsesocial.com/papers/69730f78c8125b09b0d1f4b9https://doi.org/10.1093/cid/ciag005
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