Is Iron Combined With Lactoferrin More Effective Than Iron Alone in Improving Iron Metabolism in Children With or Without Anemia? A Systematic Review and Meta-analysis of Controlled Clinical Trials.

Key Points

• The study aims to determine if combining iron with lactoferrin is more effective than iron alone in enhancing iron metabolism in children.
• Conducted a systematic review and meta-analysis of controlled clinical trials.
• Included studies involving children with and without anemia.
• Analyzed the effects on iron metabolism with and without lactoferrin.
• Iron combined with lactoferrin showed a significant improvement in iron levels compared to iron alone.
• Children receiving the combination had enhanced iron absorption and metabolism.
• Findings suggest that lactoferrin may boost the effect of iron supplementation.