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Synapse
January 24, 20260 citations

Passive leg raising and microvascular skin blood flow to predict peripheral tissue perfusion fluid responsiveness.

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AMAlexandra MorinCMChloé McAvoyJBJ J Bernier

Key Points

  • To determine if passive leg raising can predict skin blood flow changes in septic patients during volume expansion.
  • Conducted in septic patients
  • Measured skin blood flow changes during passive leg raising
  • Evaluated responsiveness to subsequent volume expansion
  • Passive leg raising induced significant changes in skin blood flow
  • Changes reliably predicted peripheral microvascular responsiveness
  • Suggests potential for personalized fluid strategies

Abstract

In septic patients, PLR-induced changes in SBF reliably predict peripheral microvascular responsiveness to a subsequent volume expansion. This simple, non-invasive approach may facilitate personalized fluid strategies aimed at optimizing microvascular tissue perfusion.

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Cite This Study

Morin et al. (2026) studied this question.

synapsesocial.com/papers/6974610cbb9d90c67120aecahttps://doi.org/10.1186/s13054-026-05852-x
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