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January 24, 20260 citations

Air pollution-related metabolic profiles and subsequent heart failure risk.

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CYChaojun YangZFZhixing FanJZJ Zhang

Key Points

  • The research investigates the relationship between air pollution and heart failure risk, focusing on metabolic changes.
  • Observational analysis of air pollution exposure and heart failure incidence.
  • Evaluation of metabolic profiles in relation to cardiovascular outcomes.
  • Statistical analysis to determine the association between pollution and heart failure.
  • Increased exposure to air pollution correlates with a higher risk of developing heart failure.
  • Identified specific metabolic perturbations linked to air pollution that may mediate this risk.

Abstract

Air pollution was associated with increased HF risk, with metabolic perturbations appearing to play a mediating role. These metabolic signatures provide insights into potential mechanisms linking air pollution to cardiovascular outcomes.

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69746126bb9d90c67120b00dhttps://doi.org/10.1136/heartjnl-2025-326668
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