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January 24, 2026HIV Research & Clinical Practice0 citationsOpen Access

Utility of the brief Patient Health Questionnaire-2 and Generalized Anxiety Disorder-2 screeners for depression and generalized anxiety symptom identification in people with human immunodeficiency virus

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GLGrace Yeeun LeeThe University of SydneyMLMaria C. LatimerJohns Hopkins UniversitySKSharon M. KellyJohns Hopkins University

Key Points

  • The study aims to assess the effectiveness of PHQ-2 and GAD-2 screeners in identifying depression and anxiety symptoms in individuals with HIV.
  • Conducted in clinical settings specializing in HIV care.
  • Utilized PHQ-2 and GAD-2 screening tools with defined cut points.
  • Evaluated the potential for integrating these screeners into routine health care.
  • Detected depression and anxiety symptoms effectively using PHQ-2 and GAD-2.
  • Highlights the importance of simplified detection for individuals with HIV needing further evaluation.

Abstract

In the context of HIV care provision in busy clinical settings, our findings indicate that implementation of the PHQ-2 (cut point ≥ 2 or ≥3) and GAD-2 (cut point ≥ 3) detect depression and anxiety symptoms. The implementation of these brief screeners in routine health care settings has the potential for simplified detection of people with HIV who would benefit most from further evaluation for MHD.

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Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69746126bb9d90c67120b09chttps://doi.org/10.1080/25787489.2026.2616103
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