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January 24, 2026Ocular Immunology and Inflammation0 citations

Long-Term Outcomes of a Standardized 12-Week Oral Valganciclovir Treatment for PCR-Proven CMV Anterior Uveitis: A Retrospective Korean Cohort Study

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SPSeun Ja ParkYJYong Sok JiSPSang Woo Park

Key Points

  • The aim is to evaluate the long-term outcomes of a 12-week oral valganciclovir treatment for CMV anterior uveitis.
  • Conducted a retrospective review of patients with PCR-proven CMV anterior uveitis
  • Administered a standardized 12-week oral valganciclovir regimen
  • Monitored intraocular pressure (IOP) response and relapse rates
  • Valganciclovir was effective for initial disease control
  • Relapse after treatment discontinuation was common
  • Early IOP response may be a predictor of future relapses
  • Long-term maintenance with 2% topical ganciclovir is suggested for high-risk patients

Abstract

A standardized 12-week oral valganciclovir regimen was effective for induction but relapse after discontinuation was common. Early IOP response may predict recurrence, and prolonged maintenance with 2% topical ganciclovir could provide a practical option for high-risk patients.

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Cite This Study

Park et al. (2026) studied this question.

synapsesocial.com/papers/697461a8bb9d90c67120b7c6https://doi.org/10.1080/09273948.2025.2612117
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment outcomes in cytomegalovirus anterior uveitis2024 · 10 citations
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  3. 3Efficacy of Intravitreal Ganciclovir Injection with or without Oral Valganciclovir versus Topical 2% Ganciclovir for Cytomegalovirus Anterior Segment Infection2025 · 1 citations
  4. 4Impact of Antiviral Therapy in Cytomegalovirus-Positive Anterior Uveitis2025 · 2 citations
  5. 5Standardization of Uveitis Nomenclature for Reporting Clinical Data. Results of the First International Workshop2005 · 4,418 citations