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January 25, 2026Clinical Case Reports1 citationsOpen Access

Langerhans Cell Histiocytosis Presenting With Diabetes Insipidus in a 2 Years Old Child: A Case Report

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KYKidus Geabriel YohannesNKNibretu Bekele KassaZTZerubabel Girma Tesso

Key Points

  • The case report aims to emphasize the importance of considering Langerhans cell histiocytosis in young children presenting with specific symptoms.
  • Presentation of a clinical case involving a 2-year-old child
  • Assessment of symptoms including failure to thrive, diabetes insipidus, and skin lesions
  • Discussion of diagnosis and management strategies
  • Identification of Langerhans cell histiocytosis as a potential cause of diabetes insipidus
  • Early management improved the child's condition
  • Highlighting the importance of recognizing key symptoms for timely intervention

Abstract

ABSTRACT This case report highlights that Langerhans cell histiocytosis should be suspected in the differential diagnosis for children who exhibit failure to thrive, diabetes insipidus, and skin lesions. Early recognition and timely management are crucial for preventing irreversible hypothalamic–pituitary damage and improving outcomes.

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Cite This Study

Yohannes et al. (2026) studied this question.

synapsesocial.com/papers/6975b20efeba4585c2d6d971https://doi.org/10.1002/ccr3.71904
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