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January 25, 2026Cancer Medicine0 citationsOpen Access

Racial and Ethnic Disparities in Pharmacologic and Non‐Pharmacologic Pain Management Among Older Cancer Survivors

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OBOindrila BhattacharyyaMEMohamed I. ElsaidMLMichael S. Lyons

Key Points

  • To examine the differences in pharmacologic and non-pharmacologic pain management among older cancer survivors based on racial and ethnic backgrounds.
  • Created a cohort of older cancer survivors (≥ 66 years) from SEER-Medicare claims data (2007-2016)
  • Focused on pain treatment incidence within 90 days post-diagnosis
  • Measured racial disparities using adjusted incidence ratios and linear regression for treatment comparisons
  • Non-Hispanic Black, Hispanic-Latino, and Asian/Pacific Islander survivors received less pain treatment than non-Hispanic Whites
  • Males of Other race-ethnicity had lower opioid usage compared to non-Hispanic White males
  • Racial minorities experienced lower opioid doses for longer durations, but higher non-opioid doses for shorter durations

Abstract

ABSTRACT Introduction Pain is common among cancer survivors and often managed with medication; however, racial‐ethnic disparities persist in pain treatment. Given inadequate data on pharmacologic and non‐pharmacologic pain management among minoritized cancer survivors, we investigated these patterns using the SEER‐Medicare claims linked database. Methods An incident cancer diagnosis cohort (≥ 66 years) was created from 2007 to 2016. The primary outcome was incidence of pain treatment (pharmacologic and non‐pharmacologic) within 90 days post‐diagnosis. Racial disparities were measured as adjusted incidence ratios for treatment using Poisson regression and adjusted differences in supply days and doses using linear regression, comparing non‐Hispanic Black (nHB), Hispanic‐Latino (LatinX), Asian/Pacific Islander (API), and Others to non‐Hispanic White (nHW). Models were adjusted for demographic and clinical variables. Results Among 300,048 survivors—nHW (72.9%), nHB (9.6%), LatinX (8.8%), API (7.3%), Others (1.4%)—nHB (aIR = 0.96, 95% CI, 0.95–0.98), API (aIR = 0.96, 95% CI, 0.95–0.98) and Others (aIR = 0.91, 95% CI, 0.87–0.94) used less pain treatment overall than nHW. Opioids (80% of treatments) were less frequently utilized by males of the Other race‐ethnicity group (aIR = 0.75, 95% CI, 0.70–0.81), compared to nHW males. For non‐opioids, nHB males (aIR: 0.84, 95% CI, 0.79–0.88) were less likely to use these therapies as compared to nHW males. Non‐pharmacological treatments were less utilized by nHB (aIR = 0.65, 95% CI, 0.62–0.69) and LatinX survivors (aIR = 0.69, 95% CI, 0.65–0.73), as compared to nHWs. Minority survivors received lower opioid doses for longer durations, but higher non‐opioid doses for shorter durations. Conclusion There are considerable racial‐ethnic disparities in the utilization of pharmacologic and non‐pharmacologic pain treatments among cancer survivors. Future research should explore the drivers of these inequities.

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Cite This Study

Bhattacharyya et al. (2026) studied this question.

synapsesocial.com/papers/6975b36bfeba4585c2d6ed66https://doi.org/10.1002/cam4.71536
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