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February 2, 20260 citationsOpen Access

The Law of Pathological Stability: A Dynamical Definition of Disease and Cure

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HRHarsha Vardhan Routhu

Key Points

  • This work aims to redefine disease and cure through a dynamic framework that focuses on system stability.
  • Proposed a unifying theoretical framework called the Law of Pathological Stability.
  • Analyzed disease persistence in the context of nonlinear biological systems.
  • Examined the nature of stable pathological attractors and their role in disease dynamics.
  • Established that disease is represented by stable pathological system states.
  • Demonstrated that cure involves the destabilization of these states rather than eliminating components.
  • Provided insights into relapse and resistance as natural outcomes within this framework.

Abstract

This work proposes a unifying theoretical framework—the Law of Pathological Stability—which reframes disease not as the presence of abnormal components, but as the existence of stable pathological system states sustained by biological dynamics. We demonstrate that disease persistence is governed by the stability of pathological attractors within nonlinear biological systems, and that cure corresponds not to component elimination, but to irreversible destabilization of these attractors. This formulation is substrate-independent, scale-invariant, and disease-agnostic. It provides a precise definition of cure, explains relapse and resistance as dynamical inevitabilities rather than treatment failures, and establishes principled boundaries on curability.

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Cite This Study

Harsha Vardhan Routhu (2026) studied this question.

synapsesocial.com/papers/6980fd9dc1c9540dea80f533https://doi.org/10.5281/zenodo.18410880
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