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February 2, 2026Journal of International Medical Research0 citationsOpen Access

A rare case of ectopic origin of the left anterior descending artery from the right coronary sinus misdiagnosed as a chronic total occlusion lesion

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WJWencai JiangSZShiheng ZhouHYHanxuan Yang

Key Points

  • To present a rare instance of a left anterior descending artery originating from the right coronary sinus and the challenges in diagnosis.
  • Detailed angiographic evaluation of coronary arteries
  • Comparison with typical presentations of coronary occlusions
  • Analysis of clinical history and imaging results
  • The left anterior descending artery was found to originate from the right coronary sinus.
  • It was initially misinterpreted as a chronic total occlusion.
  • This case represents the first documented instance of this specific ectopic artery configuration.

Abstract

We report a rare case of a left anterior descending artery originating from the right coronary sinus. The original left anterior descending artery was small and appeared occluded; it was initially misdiagnosed as a chronic total occlusion lesion. However, a displaced left anterior descending artery was identified during angiographic evaluation. Although a left main coronary artery arising from the right coronary sinus is uncommon (prevalence of 0.03%), to the best of our knowledge, this is the first reported case of an ectopic left anterior descending artery originating from the right coronary sinus.

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Cite This Study

Jiang et al. (2026) studied this question.

synapsesocial.com/papers/6980fefbc1c9540dea8119a4https://doi.org/10.1177/03000605261416659
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