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February 2, 2026The International Journal of Tuberculosis and Lung Disease0 citations

Spatiotemporal and risk factor analysis of drug-sensitive and drug-resistant TB in West Java, 2020–2022

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NWN.H.K. WardaniKTK.D. Tjia

Key Points

  • This analysis investigates the distribution and associated risk factors of TB cases in West Java from 2020 to 2022.
  • Cohort retrospective study with 302,057 TB cases from the National Tuberculosis Surveillance System
  • Spatiotemporal mapping performed alongside Global and Local Moran’s I statistics
  • Poisson regression used to identify risk factors for drug-resistant TB
  • TB cases increased over the study period, peaking in 2022
  • Bogor Regency had the highest burden of both drug-sensitive and drug-resistant TB
  • TB cases were spatially clustered, confirmed by Global Moran’s I
  • High-burden clusters identified in Kota Bekasi, Bogor, and Bandung
  • Resuming treatment after loss to follow-up posed a 29-fold higher risk for developing drug-resistant TB

Abstract

OBJECTIVEWest Java reports the highest number of TB cases in Indonesia. This study aimed to assess the spatiotemporal distribution and risk factors associated with TB in West Java from 2020 to 2022.DESIGNWe conducted a cohort retrospective study using 302,057 TB cases, including 3,631 drug-resistant TB (DR-TB) cases, obtained from the National Tuberculosis Surveillance System. We performed spatiotemporal mapping, while spatial autocorrelation was assessed through Global and Local Moran’s I statistics. We performed Poisson regression to identify risk factors for DR-TB.RESULTSWe observed an increasing trend in TB cases during the study period, peaking in 2022. Bogor Regency consistently had the highest burden of both drug-sensitive TB and DR-TB. Global Moran’s I confirmed that TB cases were spatially clustered rather than randomly distributed. Local Moran’s I revealed high-burden clusters in Kota Bekasi, Bogor, and Bandung. Several variables were significantly associated with DR-TB, with the highest risk observed among patients who resumed treatment after loss to follow-up (relative risk = 29.0, 95% confidence interval: 26.4–31.9).CONCLUSIONThis study highlights a growing and spatially clustered TB burden in West Java. Targeted interventions focusing on high-risk populations and districts are essential to strengthen TB control strategies.

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Cite This Study

Wardani et al. (2026) studied this question.

synapsesocial.com/papers/6980ff49c1c9540dea8121eehttps://doi.org/10.5588/ijtld.25.0404
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