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February 2, 20260 citationsOpen Access

Simplified Knee MRI ‘Sagittal Tibial Epi-Physis (STEP)’ Shorthand for Skeletal Age Assessment in Pediatric Patients with ACL Injury

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AGA. GrassiUniversity of L'AquilaCRClaudio RossiUniversity of SienaLALuca AmbrosiniIstituto Ortopedico Rizzoli

Key Points

  • The study aims to develop and validate a simplified MRI-based method for assessing skeletal age in pediatric patients with ACL injuries.
  • Conducted a prospective study of 130 knee MRIs from skeletally immature patients with ACL injuries.
  • Developed the STEP Shorthand based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis.
  • Validated the method by having four raters assess MRIs using STEP and existing shorthand atlases, measuring reliability and correlation with chronological age.
  • The STEP Shorthand showed a strong correlation with chronological age (rho = 0.890, p < 0.001).
  • High inter-rater reliability was observed, comparable to established shorthand methods.
  • Utilizing sagittal T1-weighted MRI allowed for simplified and consistent assessment across raters of different expertise levels.

Abstract

Objectives: To develop a simplified MRI-based shorthand assessment method, referred to as the Sagittal Tibial Epi-Physis (STEP) Shorthand, for skeletal age assessment in skeletally immature patients with anterior cruciate ligament (ACL) injuries. This study aimed to elaborate a single-plane MRI-based skeletal age estimation tool and to explore its feasibility and inter-rater reliability in comparison with existing MRI-based shorthands. Methods: This prospective study included 130 knee MRIs (79% males) from 97 skeletally immature patients (overall average age of 14.0 ± 2.1 years) with ACL injuries treated between February 2022 and January 2025. A new shorthand assessment method was developed based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis. A validation cohort of 74 MRIs was independently evaluated by four raters with different levels of expertise using the STEP, Meza, and Politzer shorthand atlases. Inter-rater reliability (ICC), intra-rater agreement (Cohen’s kappa), and association with chronological age (Spearman rho) were calculated. Results: The STEP Shorthand tool demonstrated a strong association with chronological age (rho = 0.890, p < 0.001) with consistent associations across sex subgroups. Inter-rater reliability was high and comparable to established MRI-based shorthands. The use of a focused sagittal T1-weighted evaluation allowed for a simplified and reproducible assessment across raters with varying experience levels. Conclusions: The STEP Shorthand represents a pragmatic and reliable tool for MRI-based skeletal age assessment in pediatric and adolescent patients with ACL injuries. The STEP Shorthand can support timely decision-making in surgical planning and enhance standardization across different levels of clinical expertise.

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Cite This Study

Grassi et al. (2026) studied this question.

synapsesocial.com/papers/6980ffe7c1c9540dea812cf7https://doi.org/10.3390/diagnostics16030442
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Simplified Method for Assessing Bone Age in Adolescents2026
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  5. 5Is the Greulich and Pyle Bone Atlas Suitable When Measuring Bone Age for Pediatric ACL Reconstruction in the Modern US Population? Analysis Within the PLUTO Prospective Multicenter Cohort Study2026