Bilateral acute angle closure glaucoma (AACG) is an uncommon ophthalmic emergency which can occur due to pupillary block or ciliochoroidal effusion. This can occur due to underlying risk factors which can be exacerbated with drugs in widespread use such as antidepressants – evidence with drugs such as Citalopram, Paroxetine being higher and substantially rarer in Sertraline. We report a case of a 74-year-old female who developed bilateral AACG 4 days after Sertraline initiation, who also had hyponatremia. Though antiglaucoma medications reduced the intraocular pressure, it was brought under control further only on cessation of the drug and hyponatremia correction. Unusual causes such as the above should not be overlooked, and multidisciplinary management is essential in preventing irreversible complications.
Moses et al. (2026) studied this question.