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February 5, 2026Food & Function1 citations

Water-soluble tomato concentrate alleviates neuron apoptosis though activating ERK/CREB/BDNF signaling pathway in ischemic stroke

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LZLiang ZhouMYMiao YuYZYunqi Zhang

Key Points

  • The research aims to investigate how water-soluble tomato concentrate influences neuron apoptosis and the associated signaling pathways in ischemic stroke.
  • Utilized water-soluble tomato concentrate as an intervention
  • Examined effects on neuron apoptosis
  • Analyzed activation of ERK/CREB/BDNF signaling pathway
  • Conducted experiments in a controlled setting
  • Water-soluble tomato concentrate significantly reduces neuron apoptosis
  • Activation of the ERK/CREB/BDNF pathway is observed
  • Neuroprotective effects are established in ischemic conditions

Abstract

Ischemic stroke is a leading cause of mortality and disability worldwide, and there is an urgent need for safe dietary agents with neuroprotective potential. Water-soluble tomato concentrate (WSTC), a tomato-derived...

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/698434a6f1d9ada3c1fb2fdehttps://doi.org/10.1039/d5fo05487g
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